Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
Online ISSN : 1882-2738
Print ISSN : 0914-2649
ISSN-L : 0914-2649
Asthma and Chlamydophila pneumoniae infection
Kazunobu Ouchi
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2010 Volume 24 Issue 1 Pages 75-86

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Abstract
Chlamydophila pneumoniae causes acute human infection which is followed by asthma attack and persistent infection which may increase chronic airway inflammation of asthma. There have been a lot of substantial evidences supporting the association between Chlamydophila pneumoniae infection and asthma. Many researchers reported antibiotics treatment improved asthma symptoms and pulmonary functions in chronic stable asthma. Several reports showed antibiotic treatment favored asthma symptoms and pulmonary functions in acute exacerbation of asthma. We need further evidences for supporting routine antibiotic treatment for asthma patients. At this time, it is better to choose antibiotics, such as macrolides which are effective against Chlamydophila pneumonia when patients need antibitotics.
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© 2010 Japanese Society of Pediatric Allergy and Clinical Immunology
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