Abstract
Chlamydophila pneumoniae causes acute human infection which is followed by asthma attack and persistent infection which may increase chronic airway inflammation of asthma. There have been a lot of substantial evidences supporting the association between Chlamydophila pneumoniae infection and asthma. Many researchers reported antibiotics treatment improved asthma symptoms and pulmonary functions in chronic stable asthma. Several reports showed antibiotic treatment favored asthma symptoms and pulmonary functions in acute exacerbation of asthma. We need further evidences for supporting routine antibiotic treatment for asthma patients. At this time, it is better to choose antibiotics, such as macrolides which are effective against Chlamydophila pneumonia when patients need antibitotics.