Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
Online ISSN : 1882-2738
Print ISSN : 0914-2649
ISSN-L : 0914-2649
Change of the airway hypersensitivity in the infants before and after the treatment of swallowing abnormalities which causes infantile wheeze
Daisuke HayashiHiroshi OdajimaNaoyuki KandoYouko MurakamiZyunichirou TezukaChikako MotomuraKenji OkadaRumiko ShibataSankei Nishima
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2010 Volume 24 Issue 2 Pages 225-230

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Abstract

Background; Intervention to swallowing abnormalities may be effective against intractable infants wheeze, but change of airway hypersensitivity before and after the treatment is not reported. We observed change of the airway hypersensitivity in two cases whose swallowing abnormalities were considered as a cause of wheeze.
Case 1; A one year and eight months old boy was admitted because of wheezing. Swallowing abnormalities was found on examination of Videofluorography.
He was treated with thickened food and asthma medications. Seven months later Videofluorography showed that swallowing abnormality was not recognized with thickened food, and the respiratory threshold of acetylcholine(RT-Ach) was improved from 156μg/ml to 2,500 μg/ml.
Case 2; A 8 months old boy with wheezing. Swallowing abnormalities was found on examination of Videofluorography. He did not use the asthma medications after admission.
One year later Videofluorography showed that swallowing abnormality was not recognized with thickened food and the RT-Ach was improved from 78 μg/ml to 625 μg/ml.
Conclusions; Airway hypersensitivity with infantile wheeze due to swallowing abnormality might be improved by intervention with thickened food to swallowing abnormality.

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© 2010 Japanese Society of Pediatric Allergy and Clinical Immunology
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