Abstract
As for food allergens, the Japanese Ministry of Health Labour and Welfare (MHLW) made a decision for mandatory labeling of foods containing allergenic ingredients in 2001. Egg, milk, wheat, buckwheat and peanut, and most recently shrimp and crab require mandatory labeling. The MHLW announced the Japanese official method for the detection of specific allergenic ingredients in a ministry notification. More recently, many cases have been reported that patients who have been percutaneously sensitized by hydrolyzed wheat proteins experienced wheat-dependent exercise-induced anaphylaxis after ingestion of normal wheat products. From now on, we also should pay attention to the sensitization route of food allergens.
