Abstract
The histamine release test is in vivo inspection using the basophil. Unlike a food challenge test, there is not the risk of the anaphylactic shock. This test is inspection to evaluate the release of the chemical mediator by the degranulation through IgE-dependent immediate allergic reaction. This histamine release test is effective in the case of food allergy of an egg white, milk and wheat. In addition, there is less pseudo-positive reaction than RAST, and usefulness is high as inspection to cancellation of elimination diet. In Japan, An insurance application is accepted and can carry it out by an examination of outside orders such as SRL. However, evidence of the histamine release test is not enough, and future results of research are expected.
