Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
Online ISSN : 1882-2738
Print ISSN : 0914-2649
ISSN-L : 0914-2649
A case of the dietary protein proctocolitis
Mika TakeshitaSatoshi SatoMasako ChiyotandaTaro MiuraMiki SatoRyuhei NagaoMasanobu Ushio
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2015 Volume 29 Issue 1 Pages 108-112

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Abstract
Gastrointestinal food allergy in newborns and infants is usually caused by cow's milk. Here, we describe a case of an infant who presented with continuous bloody stool. Contrast enema showed an irregular narrowing of the intestinal lumen from the rectum to the sigmoid colon. The infant tested negative for serum IgE for cow's milk and its proteins, namely, casein, α-lactalbumin, and β-lactoglobulin. The allergen-specific lymphocyte stimulation tests for casein and lactoglobulin were positive. Upon cessation of the cow's milk-based formula, the infant's bloody stool improved. This study suggests the importance of not only making the correct diagnosis of food allergy but also knowing its gastrointestinal manifestations.
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© 2015 Japanese Society of Pediatric Allergy and Clinical Immunology
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