Abstract
Objective: To investigate the effects of ingestion methods in oral food challenge tests for hen's eggs and cow's milk on the associated symptoms and treatment. Method: While maintaining the total challenge dose, a dose titration method of 5 installments every 15 minutes (5-installment method) was changed to 3 installments every 30 minutes (3-installment method). The results of 126 positive 5-installment hen's egg challenge tests and 108 positive 3-installment tests were reviewed retrospectively and compared. In addition, the results of 17 positive 5-installment cow's milk challenge tests and 23 positive 3-installment tests were reviewed retrospectively and compared. Results: There was no difference in the rate of symptoms induced or treatment required between the 5-installment and 3-installment methods. Furthermore, there was no difference in the severity of symptoms induced between the 5-installment and 3-installment methods. Conclusion: We believe that the 3-installment method is as safe as the 5-installment method and a more convenient way to conduct the oral food challenge test.
