Abstract
Tree nuts are one of the most important causes of food allergy. Many patients develop the allergy during childhood and it is difficult to acquire tolerance. The allergy symptoms are also often very severe. In recent years, the relationship between individual allergens in crude extracts (allergen components) and clinical symptoms have been analyzed. It is also important to understand the correlation of tree nut allergens with clinical symptoms and their cross-reactivity at the component level for future clinical diagnosis and treatment. Here, an overview of the seed storage protein as an important allergen component of tree nuts, their molecular structure and similarities are discussed.