2018 Volume 32 Issue 2 Pages 258-270
Allergic conjunctivitis disease are conjunctival inflammatory diseases caused by type Ⅰ allergic reactions. In this review, we will describe mainly allergic conjunctivitis diseases seen in children. Allergic conjunctivitis diseases can be classified into four categories as follows : allergic conjunctivitis (seasonal/perennial), atopic keratoconjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis. Atopic keratoconjunctivitis and vernal keratoconjunctivitis are severe diseases in children and are accompanied with conjunctival proliferation. In cases with severe allergic conjunctivitis disease, anti-allergic ophthalmic solution is used in combination with immunosuppressive and steroid ophthalmic solution. During treatment with steroids, it is necessary to pay attention to the onset of glaucoma due to elevated intraocular pressure as a side effect of steroid. Measurement of serum and tear antigen-specific IgE can be effective for diagnosis of allergic conjunctivitis diseases. Specific immunotherapy using the identified antigen can be effective in reduction of symptoms in the future.