Atopic dermatitis as the origin of allergic march

Abstract

 Allergic march refers to the natural history or typical progression of allergic diseases that often begin early in life. These include atopic dermatitis (eczema), food allergy, allergic rhinitis (hay fever), and asthma. In most patients, atopic dermatitis is the first clinical manifestation with the highest incidence in the first year of life and those affected develop other allergic diseases such as food allergy, asthma, and allergic rhinitis later in childhood. Several cohort studies have been reported that atopic dermatitis in early infancy increases the risk of food allergy, asthma and allergic rhinitis. We expect that to prevent future allergic march, an appropriate early intervention for atopic dermatitis, which emerges at the first stage of allergic march, is important.