2022 Volume 36 Issue 5 Pages 562-567
In the Japanese Guidelines for Food Allergy (JGFA) 2021, the new chapter 12-4, 5, 6, 7 were added and updated with the latest data on allergies to peanut, tree nut, soybean, sesame, and buckwheat. Notably, the main changes were as follows: 1) "Natural history for each food" was added and summarized in a table; 2) Detailed explanation of "component-resolved diagnosis"; 3) "Diagnostic usefulness of buckwheat allergy" was added and summarized in a table. Since the late 2010s, the prevalence of allergies to tree nuts, especially walnuts and cashews, has been increasing remarkably in Japan. Walnuts are slated to be added to the mandatory labeling of specified ingredients. Seeds are undergoing some changes in allergy prevalence and diagnosis, and we hope that this guideline will help improve food allergy practices.