Abstract
Prediction and prevention of allergy is thought to be most important, for pediatric allergologists. And the determination of specific IgE in infancy is recently reported to be useful for the purpose of this prediction, besides the family history and the determination of cord blood IgE levels, proposed before.
I proposed, several years before, the standard values of serum IgE levels in infants and children, and proposed the prediction of future allergy with total serum IgE levels. At this time, I compared the specificity and sensitivity of the prediction with specific IgE values, to those with total serum IgE levels.
The prediction with specific IgE values for several kinds of antigen, used in ordinary clinical activities, was showed to be usuful to a certain degree. However, when the standard values of serum IgE levels, I proposed before, is applied, the prediction with total serum IgE levels was proved to be more precise, for the prediction of the future allergic sensitization.
