Abstract
Respiratory syncytial Virus (RSV) infection is the major cause of bronchiolitis in infants and also it is the most important respiratory tract pathogen of early childhood. We experienced 166 RSV positive cases, and about 10% of them, 19 cases had recurrent RSV infections. We examined the clinical features of these 19 chirdren with bronchial asthma who had recurrent RSV infections. Ashma severity score according to the criteria of the Japanese Research Group for Pediatric Allergy, worsened after recurrent RSV infections. In first RSV infection, six cases had first episode of wheeze and all of them was diagnosed as ashma after first RSV infection. RSV infection is supposed to be act as the trigger factor and also worsening factor of bronchial ashma, but on the other hand RSV infection does not seem to affect IgE production.
