A PROPOSAL ABOUT THEOPHYLLINE THERAPY FROM PHARMACOKINETIC ANALYSES

(II) IN CASES OF ORAL ADMINISTRATION OF SUSTAINEDRELEASE THEOPHYLLINE PREPARATION

Abstract

During the “Round the Clock” therapy, using sutained-release theophylline preparation, it is important to monitor the blood theophylline lvels, and to analyze pharmacokineticaly and to know individuality in each patients. We accumulated data of 1756 pharmacokinetic analyses in 323 cases. And from these data, we clarified the difference of pharmacokinetic parameters in each age and sex, so we propose, here, the ideal doses of sutained-release theophylline preparatopn.