A CASE WHO REPEATED VARIOUS TYPES OF SEIZURES WHICH MIGHT BE INDUCED BY THEOPHYLLINE

Abstract

We reported a girl with asthma who had 4 episodes of various types of seizures (two episodes of persistent unconciousness seizures, persistent complex partial seizure, and generalized tonic seizure) during theophylline treatment. Although her serum theophylline levels were subtherapeutic, she was shifted from theophylline to fluticasone propionate inhalation because these seizures might be induced by theophylline. Consequently, no seizures have recurred on her. She is neurologically intact while her two elder brothers have epilepsy. More careful considerations are necessary to use theophylline for the treatment of asthma in children whose family have neurological disorders.