Are Patients After Kawasaki Disease at Increased Risk for Accelerated Vascular Remodeling?

Abstract

Kawasaki disease is an acute systemic vasculitis syndrome that primarily affects childdren, but the long-term remote effects of systemic vasculitis beyond coronary complications are unknown. Is a history of Kawasaki disease a true risk factor for future vascular complications like atherosclerosis? Unfortunately, there is insufficient evidence to answer this question. However, based on my own experience in blood vessel and inflammation research, I attempted to review the significance of the research results findings to date on Kawasaki disease vasculitis, as well as the limitations of research methods, in the hope of providing new perspectives for the next generation of researchers.