Abstract
We aimed to evaluate the caries-preventive effects of a fissure sealant containing surface reactiontype pre-reacted glass ionomer (S-PRG) filler as compared to those of 2 conventional resin-based sealants. In the sealant containing S-PRG filler, significantly higher amounts of Sr and B ions were detected relative to those in the other sealants, while a considerable amount of fluoride was also released after recharge with a high fluoride concentration. On the other hand, the conventional resinbased sealants bonded by acid etching, which caused surface defects on the enamel as subsurface lesions and showed significantly increased lesion depth, indicative of enamel demineralization. In contrast, the sealant containing S-PRG filler, which bonded by means of a self-etching primer, maintained the enamel surface integrity and inhibited enamel demineralization. There was no difference in regard to bond strength for both untreated enamel and enamel subsurface lesions among the sealants. These findings suggest that sealants containing S-PRG filler have enhanced enamel demineralization inhibiting and remineralization promoting effects in long-term dental care.