2018 Volume 56 Issue 4 Pages 466-473
A rhabdomyosarcoma is a highly malignant soft tissue tumor originating in skeletal muscle cells that have failed to completely differentiate and typically occurs during childhood. This report highlights the case of a 7-year-old girl who developed dysodontiasis as a result of treatment for a rhabdomyosarcoma. The patient was diagnosed with a rhabdomyosarcoma of the right orbit (Stage I) at the age of 2 years 6 months and was treated by removal of 80% of the conjunctiva of the rapidly enlarged tumor. Subsequently, chemotherapy was given from the age of 2 years 7 months to 4 years 6 months, while radiotherapy (total dose 45 Gy) was also administered to parts along the right side of the orbit to the maxillary sinus from the age of 2 years 8 months to 2 years 9 months. Dental orthopantomograph findings revealed microdontia of the maxillary right first premolar and mandibular left second premolar, absence of dental germs of the mandibular and maxillary right second premolars,root hypoplasia of the maxillary right and left central incisors, right lateral incisor, right canine, right first premolar, and right first molar, root dysplasia of the maxillary left lateral incisor, and hypoplasia of the maxillary right alveolar bone. Based on these findings, we consider that the remarkable tooth dysplasia and maxillary development abnormalities in this case were caused by chemotherapy and radiotherapy treatments performed for the rhabdomyosarcoma in early childhood.
