Abstract
Histochemical localization of γ-glutamyl transpeptidase (γ-GTP), and measurement of γ-GTP activity, alkaline phosphatase activity, protein, calcium and phosphorus were investigated in the tooth germ of new born rats, aged 2,6,10,14,18, and 21 days old. Developmental changes fo γ-GTP activity and its localization were observed during the early mineralization of the moalr tooth germ. The peaks of γ-GTP activity and protein were observed in 7 and 17 days old rats, but the calcium level was inversed at the same time periods. The levels of phosphorus and alkaline phosphatase activity showed periodic changes in a 3 day segment during the developmental stage.