Abstract
Tumor doubling time, that is, the time reuuired for tumor volume to become twice as large, was calculated using Gerstenberg's formula.
While histouathological referrals are ideal for diagnosis, observation on growth rates of the lesion by radiographs is interpreted as painless to the subject and useful for differentiation of benign and malignant tumors.
We recently studied patterns of calcification of the mandible in four pediatric outpatients and obtained measurment of these calcified lesions as seen on orthopantomographs by means of a computerized suuare-measurement system for indeterminate forms.
The mean value of the doubling time in this study was 9.9 months, which differed considerably from that of malignant tumors.
In addition, we found that size of the lesion is related to the growth of the individual.
