Abstract
Lidocaine hydrochloride (Xylocaine(R))h as been widely used and is considered to be a relatively safe anesthetic by the dental profession.
It has been previously reported, however, that Xylocaine(R)m ay be hazardous when used excessively, and unfavorable reaction such as subcutaneous bleeding may occur following mandibular block anesthesia.
However, the hypersensitivity which may have be caused by lidocaine (Xylocaine®) is discussed in the present paper. The cases were a 4.8 years old boy and 4.0 and 7.2 years old girl patients who has vistied the Pedodontic Clinic, Gifu College of Dentistry.
The skin reactions appeared from 6 to 24 hours after injection as erosive lesions 2.0 to 2.5 cm diameter in size.
The ulcered lesion was crusted from the margin to the center and the lesion healed completely in 2 to 3 weeks.
It may be presumed that these adverse Xylocaine(R) Arthus-like reactions, though it was not verified by intracutanious skin testing, may be caused by the preservatives and additives added in the anesthetics.