Abstract
Very few studies of caries have been conducted using mice despite the fact that mice have been used in various medical experiments. Some of the advantages of using mice are that it is possible to obtain results which are highly reliable. Mice are also very easy to keep. One of the studies of caries suggested that mice can be used as experimental models in caries reseach. In the present study, the caries susceptibility of mice of different strains was examined using mice of inbred strains.
The following were the results of the present investigation.
1)Among the mice infected with S. mutans JC-2 (serotype c), there was observed a statistical difference of 1% between the caries scores of the C3H/He strain and those of the C57BL/6, DBA/2, and C57BL/10 strains.
2) Among the mice infected with S. mutans 6715 (serotype g), there was observed a statistical difference of 1% between the caries scores of C3H/He strain and those of other strains.
3) When two groups of mice of the same strain were infected with S. mut6ns, one with serotype c and the other with serotype g, the scores of the former were higher than those of the latter. Among C57BL/6 and DBA/2 strains, there was observed a statistical difference of 1% between the scores of c-infected groups and those g-infected groups.
