Abstract
To study differences among mice strains, we investigated the development of caries on hydroxyapatite (HA) disks covered with saliva from inbred mice. Differences by strain were observed by measuring the effects of surcose independent mutans streptococci on the somatic adhesion reaction.
1) There were no difference among C3H/He, BALB/c and C57BL/10 mice, which had different biochemical genetic markers, in somatic adhesion to HA disks covered saliva.
2) In these caries experiments, C57BL/10 and BALB/c showed caries susceptibility, while C3H/He was caries resistant. We reconfirmed differences among strains in development of dental caries.
