Abstract
A cidophilic granuloma is a granulomatic lesion of infiltration by acidophilic cells, mainly proliferation of histocyte in the reticuloendothelial system. The symptom is termed as histiocytosis X, a subtype of one type of a disease such as the Letterer-Siwe's disease and the Hand-Shuller-Christian's disease. It is frequently found in older children. Also it is frequently seen in the jaw, and when the granuloma is caused in the jaw, such periodonto-inflammatory responses are observed. The X-ray findings revealed a malignant tumor, and the finding is difficult to distinguish from other diseases. Pathohistological findings are the only mean of confirmative diangosis. The first choice of method of treatment may be different according to the degree and area of the granuloma. Prognosis is good in general, but in some cases, the granuloma will be transfered to other subtype(s)of the Histiocytosis X, be recurrent, or spread more from the primary focus.
The present clinical case was a 3 year and 5 month old girl, who visited us for the main complaint of swelling of the right cheek. A single acidophilic granuloma was found in the right lower jaw. Systemic, dental and clinical findings were examined. The following findings were obtained.
1) The primary symptom was similar to that of a symptom of infiamation, and the X-ray picture was similar to that of a malignant tumor, but it was not confirmed. Pathohistological findings showed histotype cells, and acidophilic megalocytes were found. Thus, acidophilic granulocyte was suspected and diagnosed.
2) Fractions of the peripheral blood picture were all within the normal range.
3) 5 years of a terminating chemotherapy, recurrence has not been observed, and thus the prognosis is good. However, permanent dental pulp was included in the primary focus, so that the first molar formation was insufficient.
