Abstract
The purpose of this study was to investigate the urinary catecholamine concentration in cooperative children and uncooperative children during dental treatment. The subjects were 13 healthy children aged from 3 to 8 years. They received infiltration anesthesia with Citanest-Octapressin®(without catecholamine), when local anesthesia was needed during the dental treatment. The samples for analyses were urine that was taken before dental treatment and after dental treatment. Dopamine, noradrenaline and adrenaline were isolated from the urine, and quantitative analyses were performed.
The results are summarized as follows;
1) The adrenaline concentration after dental treatment was higher than before dental treatment in most cases. The increment ratio was 98.3%.
2) The dopamine and noradrenaline concentration showed no regular relationship between before dental treatment values and those after dental treatment. The average increment ratios were lower than that of adrenaline by 7.3 % in dopamine and 6.3% in noradrenaline respectively.
3) The cooperative children showed a significant difference between before dental treatment and after dental treatment in the adrenaline concentration(p<0.05). Adrenaline after dental treatment was higher than that before dental treatment. The increment ratios were 52.2% in the adrenaline, -0.5% in the noradrenaline and 11.4 % in the dopamine.
4) The uncooperative children showed significantly higher concentrations of adrenaline (p<0.01) by 172.1% and of noradrenaline (p<0.05) by 16.9% after dental treatment than before dental treatment, whereas dopamine snowed no difference by 0.8%.
5) There was a high correlation between the increment of the adrenaline concentration and the behavior of the children during dental treatment (r=0.74).