Abstract
The purpose of this study was to evaluate histopathologically the 4-META/MMA-TBB resin as a direct pulp capping material.
Fifty-three Class V or Class I deep cavity were prepared in four beagle dogs under general anesthesia. Without local anesthesia, cavity floors were intentionally perforated to expose the pulp. Sunmedical Co.4-META/MMA-TBB resin “Orthomite Super Bond” was directly applied to the exposed pulp (SB group). As the control, Neo Dental Chemical Products Ca(OH)2 medicament “Calvital” was used as a direct pulp capping agent (CV group). Both in the SB groups and in the CV groups, the cavities were lined with “Orthomite Super Bond” and filled with the Kuraray Co. composite resin “Clearfil Photo Anterior” after etching and bonding. After 14 and 30 days, the histo-pathological responses of the pulp were analyzed. The number of the cases in each of the groups was: SB-14 days (17 cases), SB-30 days (14 cases), CV-14 days (13 cases) and CV-30 days (9 cases).
1 ) Inflammatory cells infiltrated into the pulp: 4 cases (23.5%) in the SB-14 day group,8 cases (57.1%) in the SB-30 day group,5 cases (38.5%) in the CV-14 day group and 2 cases (22.2%) in the CV-30 day group.
2 ) Partial necrosis of the pulp was observed in the 2 cases (14.3%) in the SB-30 day group. Complete necrosis of the pulp was observed in the 2 cases (15.4%) in the CV-14 day group and in the 2 cases (22.2%) in the CV-30 day group.
3 ) Circulatory disturbances in the remaining pulp: 10 cases (58.8%) in the SB-14 day group,6cases (42.9%) in the SB-30 day group,6 cases (46.2%) in the CV-14 day group and 4 cases (44.4%) in the CV-30 day group.
4 ) Macrophage migration aroud the interface between pulp and capping materials: 8 cases (47.1%)in the SB-14 day group,10 cases (71.4%) in the SB-30 day group,7 cases (53.8%) in the CV-14day group and 4 cases (44.4%) in the CV-30 day group.
5 ) Dentin bridge formation: 12 cases (70.6%) in the SB-14 day group, none in the SB-30 day group,1 case (7.7%) in the CV-14 day group and 3 cases (33.3%) in the CV-30 day group.
6 ) In all of the 4 groups, the SB-14 day group showed the best histo-pathological results, however, the results of the SB-30 day group was poor.