Journal of the Japan Society for Precision Engineering, Contributed Papers
Online ISSN : 1881-8722
Print ISSN : 1348-8724
ISSN-L : 1348-8716
Paper
Predicting Genes of Cancer Outcome in Prognosis Based on SOM
Masashi FURUKAWA[in Japanese]Michiko WATANABEYukinori KAKAZU
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2006 Volume 72 Issue 2 Pages 266-270

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Abstract
Since 1981, the cancer has occupied the first cause of Japanese death. Therefore, it is an urgent matter to tackle the cancer problem. Recently, it is understood that outcome of the cancer disease in a prognosis is related to the special combination of genes. However, it is very difficult to predict the outcome of the cancer disease in a prognosis, because a huge number of genes exist and we have to explore the special combination of genes among them. This study aims at finding the special genes combination, which affects on the outcome of the cancer disease in a prognosis. Self-Organizing Maps (SOM) is applied to accomplish our aim. Namely, SOM is used to cluster genes to predict the outcome of the cancer disease. Two analysis methods are also introduced into the SOM results, because it is insufficient for SOM only to specify the combination of genes, which affects on outcome of the cancer disease. Numerical experiments present some useful information on the outcome of the cancer disease in a prognosis.
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© 2006 The Japan Society for Precision Engineering
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