2017 Volume 32 Issue 5 Pages 1468-1473
Aim: To investigate the factors related to short-term and long-term post-operative weight loss from gastrectomy for gastric cancer.
Subjects and Methods: From September 2014 to June 2015, 104 patients who underwent elective gastrectomy or total gastrectomy for gastric cancer in our hospital were followed-up for 6 months to examine weight loss and then were investigated retrospectively. Univariate analysis using Fisher's exact test, t test, Mann-Whitney U test, and multivariate regression analysis were performed to correlate variables with weight loss. P < 0.05 was defined as being statistically significant.
Results: There was a statistically significant correlation between pre-operative chemotherapy and shortterm weight loss (P = 0.013) in multivariate analysis. With regard to long-term weight loss, there were statistically significant correlations between both the skeletal muscle mass index reduction rate (P = 0.020) and the short-term weight loss (P < 0.001) in multivariate analysis.
Conclusion: Pre-operative chemotherapy was associated with short-term weight loss. Short-term weight loss and the skeletal muscle mass index reduction rate also affected long-term weight loss.
