1982 Volume 31 Issue 2 Pages 69-81
The purpose of this study is to clarify influence of physical load on the liver function during an intensive athletic training camp, especially from the aspect of clearance ability of indocyaine green by the liver. The experimental subjects consisted of 12 male students in a track and field clubs, aged 16 to 20 years, who were subjected to a 7-day track and field training.
Their physiological functions such as Flicker fusion frequency, Patellar refrex and Near point were measured every day during the training period, and ICG test and measurements of various blood components and serum enzymes were conducted early in the morning at the basal condition, on the firstday, the intermediate (4th day), and the final day (7th day) of the training period.
The experimental results were obtaind as below.
1. Judging from the variation of the physiological function and blood values, it was surely assumed that the physical stress was strongest on the intermediate day of training period.
2. The activation of serum enzymes (GOT, GPT, LDH, CPK) showed a rapid rise on the intermediate day and then a slight decline toward the final day.
3. Concerning ICG test, serum disapperrance rate of ICG (K) on the final day lowered significantly, comparing with that on the first day, while 15-minites retention rate (R5) rose significantly. The above results verified a delay of ICG clerance in the liver.
4. Significant correlations were found between the changes of both R15 and K from the first to the final day and those of GOT, LDH and near point, respectively.
5. ICG test conducted for the other three subjects on the intermediate day, on the final day and 2 weeks after the training period, revealed that K value on the intermediate day was lower than that on the final day and the value 2 weeks after was highest.
This result suggests that the liver function was lowest on the intermediate day, corresponding to the changes of the physiological function mentioned in 1), of serum enzymes mentioned in 2), and behavior of leukocytes measured by Ishihara on the same subjects. The above results obtained by the present study suggest that the lowering of liver function participates closely in stress and fatigue due to the heavy athletic training.