2017 Volume 23 Issue 2 Pages 161-166
Background: End-stage liver disease is often accompanied with portal vein stenosis (PVS) or thrombosis (PVT). The presence of PVS/PVT is sometimes considered as a contraindication to liver transplantation because of difficulty in portal vein reconstruction. In this study, the outcomes of patients with PVS/PVT receiving liver transplantation was evaluated.
Patients and Methods: Clinical features of 151 adult patients receiving liver transplantation in our hospital were retrospectively examined. Among them, 28 patients (18.5%) had PVS/PVT and 12 patients were given modified portal vein reconstruction; cavoportal hemitransposition in 1, jump graft in 2 and renoportal anastomosis in 9.
Results: Postoperative courses were satisfactory in 12 recipients receiving portal vein reconstruction, in whom liver function was maintained. There is no significant difference in rate of change in estimated Glomerular Filtration Rate (eGFR) between the modified portal vein reconstruction group and the control group. The survival rates of patients receiving modified portal vein reconstruction at 1, 5 and 10 years later were 91.7%, 91.7% and 76.4%, respectively; the rates showed no difference comparing to those in control group.
Conclusion: liver transplantation with modified portal vein reconstruction was a life-saving and safe technique for patients with end-stage liver diseases complicating PVS/PVT.
