Shoyakugaku Zasshi
Online ISSN : 2433-8486
Print ISSN : 1349-9114
Originals
Studies on Arecae Semen: Development of HPLC Analysis of Alkaloids and Application of the Analysis to Japanese Market Samples
Yutaka Yamamoto, Kayoko Tokura, Keiko Arimoto, Michiho Ito, Mamoru Okasaka, Akiko Kawabata, Eiji Sakai, Yasuo Shimada, Yoshitaka Takai, Takaomi Tagami, Ryohei Nomura, Masataka Moriyasu, Tsuguo Yokokura, Masato Yoshikawa
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Keywords: Arecae Semen, arecaidine, arecoline, guvacine, HPLC, quantitative analysis
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2016 Volume 70 Issue 1 Pages 17-26

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Abstract

According to the Japanese Pharmacopoeia Sixteenth Edition (JP16), the origin of Arecae Semen is the seed of Areca catechu Linné (Palmae). Arecae Semen is used as an ingredient of Kampo formulae such as Kumibinroto and Nyoshinsan. The seed contains alkaloids such as arecaidine, arecoline, guvacoline and guvacine. However, no quantitative test for Arecae Semen is designated in JP16. In this study, an analytical method using HPLC for arecaidine, arecoline and guvacine in Arecae Semen was elaborated, and was performed on the market samples.

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© 2018 The Japanese Society of Pharmacognosy
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