Abstract
Objective: We investigated the intellectual function of ten pediatric patients after treatment of medulloblastoma.
Methods: To evaluate the intellectual function, we retrospectively analyzed the scores of the participants in the Japanese version of the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV). The median age at the time of diagnosis was 5.0 years. The median duration from the end of treatment to an examination was 59.5 months. We compared the scores of 4 indexes in all the patients, and compared the test results at two points. We examined the effects of hydrocephalus or radiation exposure symptoms as complications on the scores of the 4 indexes.
Results: The processing speed index score was lower than the others (FSIQ, 92.0; VCI, 90.0; PRI, 97.5; WMI, 95.5; PSI, 84.5). There was no significant difference between those two periods in the WISC-IV quotients of five children. The effects of both the hydrocephalus and radiation exposure symptoms on the scores of 4 indexes of WISC-IV did not reveal a statistically significant difference.
Conclusion: We should evaluate not only the change in the intellectual function, but also the educational outcome, which indicates social reintegration.
