2018 Volume 55 Issue 3 Pages 304-308
The treatment of bilateral Wilms’ tumors aims at preserving renal function. We report the cases of two patients with bilateral Wilms’ tumors, who successfully underwent nephron-sparing surgery following chemotherapy. Patient 1 was a 1-year-old girl who initially underwent bilateral renal biopsy. Patient 2 was a 2-year-old boy with WAGR syndrome who did not undergo tumor biopsy in accordance with the latest protocol. Each patient underwent chemotherapy before tumor resection, and we evaluated tumor size by imaging studies over time. Computed tomography revealed a reduction in the size of the tumors initially, and no significant changes were observed subsequently. Then, partial nephrectomies were performed. Static renal scintigraphies were performed to evaluate the renal function pre- and postoperatively. The renal function of each patient was well preserved and they are doing well without tumor recurrence. During the treatment of bilateral Wilms’ tumors, it is important to evaluate renal function and tumor size on a regular basis.
