The Japanese Journal of Pediatric Hematology / Oncology
Online ISSN : 2189-5384
Print ISSN : 2187-011X
ISSN-L : 2187-011X
Case Report
A Case of Pediatric Acute Lymphoblastic Leukemia Diagnosed with Hypopyon as Initial Symptom
Nobuhisa TakahashiHideki SanoKazuhiro MochizukiShogo KobayashiYoshihiro OharaMinoru FurutaAtsushi Kikuta
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Keywords: children, ALL, hypopyon
JOURNAL FREE ACCESS

2019 Volume 56 Issue 1 Pages 57-60

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Abstract

Hypopyon commonly manifests in infections and autoimmune diseases such as Behcet’s disease, but rarely occurs in patients with acute leukemia. In this case, a 5-year-old girl was diagnosed as having hypopyon by a local physician and referred to our hospital for a definitive diagnosis. She was diagnosed as having B precursor acute lymphoblastic leukemia (ALL), with central nervous system invasion. The patient underwent iridectomy to decrease the intraocular pressure in the left eye, and ALL cells were observed in the iris. Following treatment, she remained in complete remission for 7 years. Hypopyon in patients with acute leukemia is often observed at the time of relapse, but is rarely detected at the initial stage. Regular follow-up for recurrence is necessary owing to the limited transport of anticancer drugs to the eyes.

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© 2019 The Japanese Society of Pediatric Hematology / Oncology
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