A boy with clavicular non-Hodgkin lymphoma with sacral epidural involvement

Abstract

Pediatric non-Hodgkin lymphoma (NHL) with epidural involvement is rare, and to the best of our knowledge, no cases of NHL with sacrum involvement have been reported. We report a case of clavicular NHL with sacral epidural involvement. An 8-year-old boy was admitted with a mass extending from the right precordium to the shoulder. Fluorodeoxyglucose positron emission computed tomography revealed a mass in the right shoulder and sacral epidural involvement, and magnetic resonance imaging showed an enhanced mass in the sacrum. The patient was diagnosed as having clavicular precursor B-cell lymphoblastic lymphoma with sacral epidural involvement on the basis of a biopsy from the mass in the shoulder. He was treated according to the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) ALB-NHL03 protocol. Primary lymphoma of the bone is rare, and no cases of pediatric lymphoma with epidural involvement have been reported. He has been doing well without relapse 8 months after therapy completion.