2019 Volume 56 Issue 2 Pages 216-220
The patient was an 8-year-old girl in whom stage IV infantile neuroblastoma developed 8 months after birth. Remission was achieved after combination chemotherapy, high-dose chemotherapy with autologous stem cell transplantation, and primary tumor resection. On periodic examination 7 years after treatment completion, a 2 cm tumor was detected by abdominal ultrasonography in the pancreatic body. Since the patient was negative for various tumor markers, pancreatic solid pseudopapillary neoplasm (SPN) was suspected. Distal pancreatectomy was immediately performed and histopathological analysis of the tumor showed it to be pancreatic SPN. One year and 10 months after the surgery, no recurrence has occurred. SPN is a low-malignancy tumor, but it may invade surrounding tissue, metastasize, and recur. Thus, careful time-course observation is necessary. In our patient, the age at onset differed from that of typical SPN, suggesting the possibility of secondary cancer after treatment of neuroblastoma or metachronous double cancer. This emphasizes that long-term follow-up examinations, including imaging, is important after pediatric cancer treatment.
