2020 Volume 57 Issue 3 Pages 304-308
Adrenal cortical carcinoma (ACC) is a rare endocrine malignancy with a poor prognosis in children. A 14-year-old girl presented with bilateral leg edema, signs of Cushing’s syndrome and virilization. She underwent surgery with complete resection of a right adrenal tumor. Findings of endocrinological laboratory tests and histopathological analysis of the tumor confirmed the diagnosis of functional ACC. She was treated with a combination of oral mitotane and intravenous cytotoxic drugs. She required right pulmonary metastasectomies on two occasions at 47 and 104 months after the initial ACC diagnosis. 18F-FDG-PET/CT was valuable for detecting recurrence in the follow-up of this patient with silent clinical signs.
