2021 Volume 58 Issue 2 Pages 99-102
Reirradiation for pediatric cancer is considered in practice, but there are only a few reports on this treatment approach. In this study, we investigated the cases of patients who underwent reirradiation, including 33 patients (21%) who underwent more than one irradiation out of 158 patients treated with radiation therapy from 2013 to 2019. The results showed that brain tumors were the most frequent malignancies observed (10 patients.) Furthermore, cases of medulloblastoma patients who were reirradiated between 2015 and 2019 were examined in detail. There were three patients with relapsed medulloblastoma, all of whom were treated with 12 Gy/8 fractions of cranio-spinal irradiation, but they suffered a meningeal dissemination relapse after reirradiation. There were three patients with second cancer, glioblastoma, treated with reirradiation after treatment of medulloblastoma. These patients were irradiated with 40.05 Gy/15 fractions, but they developed early relapse and died. Reirradiation is considered to be one of the options because of reports of long-term survival, but its effectiveness needs to be investigated in the future.
