The Japanese Journal of Pediatric Hematology / Oncology
Online ISSN : 2189-5384
Print ISSN : 2187-011X
ISSN-L : 2187-011X
Case Report
A case of infant neuroblastoma managed without treatment for histopathological residual liver metastases
Seiya MatsuoKoji SuzukiToshihide YoshikawaAina YamaguchiYoshiaki ImamuraEri OgawaTatsuya OkamotoAkihiko TanizawaYusei Ohshima
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2021 Volume 58 Issue 3 Pages 301-305

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Abstract

A nine-month-old female infant with a left adrenal gland tumor was referred to our hospital. She was diagnosed as having an intermediate-risk neuroblastoma as per the Children’s Oncology Group risk classification. After five courses of multidrug chemotherapy, the primary tumor was excised and the metastatic liver tumors were biopsied. Although residual histopathological neuroblastoma cells were confirmed in both the primary tumors and liver metastases, treatment was terminated after one additional course of chemotherapy. After the treatment, magnetic resonance imaging and metaiodobenzylguanidine scintigraphy findings revealed liver metastases. The treatment ended two years and one month ago, but no recurrence has been detected since then. In the case of a neuroblastoma with favorable biological factors, it may be advisable to forgo additional treatment for residual tumor after induction therapy even when histopathological neuroblastoma cells remain.

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© 2021 The Japanese Society of Pediatric Hematology / Oncology
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