Burkitt lymphoma in a boy with Williams syndrome

Abstract

Williams syndrome (WS) is a rare disorder caused by a microdeletion on chromosome 7q11.23, and it is characterized by a specific facial dysmorphism, visuospatial deficits, and cardiovascular disease. Our patient was a 13-year-old boy who had intussusception and was diagnosed as having Murphy stage II Burkitt lymphoma. He was administered a standard combination chemotherapy and has been in complete remission for more than three years. Recently, some cases of malignant lymphoma have been noted in patients with WS. Genes at chromosome 7q11.23 may play a role in the occurrence of malignant lymphoma.