2023 Volume 60 Issue 1 Pages 57-60
Benign or malignant adrenocortical tumors are rare and difficult to diagnose. A 5-year-old girl presented with premature pubic hair; imaging confirmed a right adrenal tumor. She was diagnosed as having a functional adrenal tumor and gonadotropin-independent precocious puberty. She had no metastases and underwent total resection of the tumor. However, this tumor was judged to be malignant on the basis of the Weiss criteria and benign on the basis of the Wieneke criteria. After comprehensive morphological and immunohistochemical evaluations based on the two specific criteria and the presence of Ki-67, respectively, it was decided that postoperative chemotherapy would not be performed. A year after the surgery, no recurrence was observed, and unnecessary postoperative therapy was avoided.
