2025 Volume 62 Issue 5 Pages 342-346
Peripherally inserted central venous catheters (PICCs) are often used in pediatric patients with cancer. Although PICC-related complications, such as bloodstream infection and thrombosis, have been reported, studies on the complications associated with PICC reinsertion in the same patient remain limited. Here, we report a case of asymptomatic venous stenosis in the upper extremities after PICC reinsertion in a pediatric patient treated with chemotherapy for B-cell precursor acute lymphoblastic leukemia (ALL). The patient was successfully treated by changing the vessel for PICC insertion; however, subsequent relapse necessitated a long-term indwelling central venous catheter because PICC reinsertion was difficult. Although treatment of primary ALL may be completed by changing the vessel for PICC insertion, further evaluation is needed to assess the safety of long-term PICC use and clinical significance of asymptomatic venous stenosis after PICC placement.