Palliative Care Research
Online ISSN : 1880-5302
ISSN-L : 1880-5302
Original Research
A Retrospective Study of the Usefulness of Asenapine Sublingual Tablets for Delirium in Patients with Advanced Cancer
Toshiya Maekura Sayo AikiHiroko TamiyaIkuo KudawaraMachiko SakuraiAyumi Yoshikane
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2023 Volume 18 Issue 3 Pages 177-182

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Abstract

Purpose: To evaluate the usefulness of asenapine sublingual tablets for the treatment of delirium in patients with advanced cancer. Methods: We conducted a retrospective study using electronic medical records of patients with advanced cancer who were admitted to our hospital between October 1, 2019 and September 30, 2022 and who received asenapine sublingual tablets as treatment for delirium. The Agitation Distress Scale (ADS) was used to evaluate the degree of improvement of agitation symptoms caused by delirium. Results: Twenty patients were included in the analysis. The mean ADS(range) before treatment was 12 (4–17), and the mean ADS(range) after treatment was 7.9 (0–18), with the p-value <0.001. Conclusion: Asenapine sublingual tablets may be useful as an option for pharmacological treatment of delirium.

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© 2023 Japanese Society for Palliative Medicine
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