Nervous System in Children
Online ISSN : 2435-824X
Print ISSN : 0387-8023
A patient with pediatric diffuse pontine astrocytoma: good local control after gamma knife radiosurgery
Shin HirotaJuri KiyokawaHiroto YamaokaMariko IshikawaSatoshi KanekoMasataka YoshimuraShinji YamamotoMasaaki Yamamoto
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2021 Volume 46 Issue 4 Pages 320-325

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Abstract

This article reports a case of brainstem tumor treated by gamma knife radiosurgery (GKRS) after a pathological/genetic diagnosis. An 11-year-old boy with an extraocular movement disorder presented with a 16-mm well-defined spherical tumor protruding from the dorsal pons. An open biopsy was performed, and the histopathological diagnosis was pediatric diffuse astrocytoma, grade II, and the genetic diagnosis was K27M H3 wild type. GKRS was performed with a marginal dose of 15.00 (central dose 25.00) Gy. Post-GKRS, diplopia disappeared, and the progression of eye movement disorder stopped. A tumor size decrease was remarkable (11 mm). The patient has exhibited a stable course for 4 years. Although longer follow-up is necessary, we believe that the patient has achieved a positive outcome.

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© 2021 The Japanese Society for Pediatric Neurosurgery
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