Comparison of core promoter architecture between plants and animals

Abstract

Distribution profiles of short sequences along a promoter region has been comprehensively analyzed in silico, and hundreds of short sequences have been detected as putative promoter constituents. Based on their localization profiles, the identified sequences were classified into three groups, including TATA box and REG groups. Identified sequences of the TATA box group are consistent with the ones reported in previous studies. REG includes functionally proved cis elements, and candidates of novel cis-regulatory elements. Comparison of LDSS-positive sequences from plant and mammalian genomes will be introduced. This method does not require any biological information such as microarray data, and can detect minor elements as well.