Abstract
In eukaryotes, polyadenylation of pre-mRNAs is an essential process in the biogenesis of mRNAs. Poly(A) tract is added to the 3'-end of a processed pre-mRNA. The CLP1 protein is an important subunit of the cleavage and polyadenylation process in eukaryotic cells. In this study, the Arabidopsis CLP1 ortholog, AtCLP1, is characterized. AtCLP1 has been found to have a critical role in development by loss of function analysis using T-DNA insertion line. The homozygous atclp1 plants were embryo lethal, but the heterozygous plant, retaining their normal vegetative growth. We show the significant functions of AtCLP1 gene in plant development.
