Abstract
Peroxisomes undergo dramatic changes in size, shape, number and position within the cell, but the division process of peroxisomes has not been characterized. To better understand molecular mechanism of peroxisome division, we screened a number of Arabidopsis mutants with aberrant peroxisome morphology (apm mutants) based on the different pattern of GFP fluorescence from the parent plant, GFP-PTS1. apm mutants exhibited the tissue-specific patterns of GFP as follows, (1) elongated peroxisomes, (2) enlarged peroxisomes, (3) GFP fluorescence in the cytosol as same as in peroxisomes, and (4) different distribution of peroxisomes. We reported that the mutation in APM1 caused the morphological change to elongated peroxisomes with decrease in number, as a result of inhibition of division, and that APM1 encoded DRP3A, one of 16 dynamin-related family. In this presentation, we would like to discuss the phenotypes of another apm mutant and the double mutants with apm1.
