Abstract
Plants have higher regeneration capacity than animals. It is hence an enticing task to delineate the mechanism underneath the remarkable regeneration capacity of plants. Plants maintain the stem cell activity at roots,shoots and flowers. The homeodoman protein WUSCHEL is necessary to maintain the stem cell activity. In flower development, WUS activity is abolished after proper number of floral organ primordia is created. We show that the nuclear matrix protein GIANT KILLER is involved in negative regulation of WUS through epigenetic regulation. We also show that after the stem cell activity is abolished by ectopic GIK induction, new meristems are regenerated. I will discuss on the regulation of WUS by GIK and associated meristem regeneration.