Plant and Cell Physiology Supplement
Abstract of the Annual Meeting of JSPP 2009
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Ub/26S proteasome pathway in Arabidopsis is involved in the formation of microRNA
*Kaori SakoYuko MakiSakiko IshidaDerek GotoHiroko YamamotoAkira IkedaJunji Yamaguchi
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Pages 0424

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Abstract
Ubiquitin(Ub)/26S proteasome pathway plays an essential housekeeping role to eliminate the proteins which are damaged or misfolded. It is also essential for aspects of cellular regulation by removing short-lived regulatory proteins as a way to fine-tune homeostasis, adapt to new environments, and redirect growth and development. The 26S proteasome consists of two multisubunit complexes, 20S core particle (CP) and 19S regulatory particle (RP). The RP contains thirteen non-ATPase subunits (RPN) and a ring of six AAA-ATPase subunits (RPT).
We reported RPT2a and RPT5a deficient mutants resulted in enlarged leaves, which are caused by accelerated endoreduplication. Here we show that RPT2bRPT5a double deficient mutant reveals the similar phenotype of mutant in microRNA metabolism. The function of RPTs will be discussed in terms of microRNA biogenesis.
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© 2009 by The Japanese Society of Plant Physiologists
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