Abstract
Microorganism has one or several aquaporins. These aquaporin can transmit glycerol other than water. Aquaporin of archaebacteria and E.coli contributes to microbial growth and osmoregulation. In addition, aquaporin of yeast contributes to freezing tolerance. However, aquaporin of certain pathogenic microorganism and yeast do not have a function of water permeability. What kind of function will microbial aquaporin have? Except E. coli and yeast, most of the functions of microbial aquaporin are not elucidated. The structure and function of progenitor type of aquaporin that can transmit water and glycerol were clarified by X ray crystallography. The characteristic of aquaporin such as E. coli, yeast, Aspergillus oryzae, and cyanobacteria is reported with recent experimental results and publication of the recent thesis.