Abstract
Rab GTPase is one of the key regulators in membrane trafficking. Rab11, a broadly conserved Rab GTPase group in eukaryotes, has evolved in a unique way in plants. Plant Rab11 has notable diversity, while yeast and animals possess a few members. In Arabidopsis thaliana, 57 Rab GTPases are encoded in its genome in total, 26 of which are classified into the Rab11 group (subclassified into RabA1-RabA6). It is already known that animal Rab11 plays an important role in regulating various cellular functions. On the other hand, the precise function of plant Rab11 remains largely unknown. To reveal the plant Rab11 function, we analyzed subcellular localization of 9 members belonging to the RabA1 subgroup (RabA1a-RabA1i). We have already reported that RabA1e located on the mobile punctate structures and accumulated in the tip region of root hair cells. In this study, we performed the precise analysis of the subcellular localization of RabA1e, and found that RabA1e is almost co-localized with R-SNARE protein which functions in secretory pathway. We will also report about the novel interacting proteins with RabA1 members.
